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Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.

The beta subunit (beta c) of the receptors for human granulocyte macrophage colony stimulating factor (GM-CSF), interleukin-3 (IL-3) and interleukin-5 (IL-5) is essential for high affinity ligand-binding and signal transduction. An important feature of this subunit is its common nature, being able t...

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Bibliografski detalji
Glavni autori: Woodcock, J M, Zacharakis, B, Plaetinck, G, Bagley, C J, Qiyu, S, Hercus, T R, Tavernier, J, Lopez, A F
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC395466/
https://ncbi.nlm.nih.gov/pubmed/7957082
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