Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival

The dual specificity protein/lipid kinase, phosphoinositide 3-kinase (PI3K), promotes growth factor-mediated cell survival and is frequently deregulated in cancer. However, in contrast to canonical lipid-kinase functions, the role of PI3K protein kinase activity in regulating cell survival is unknow...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Thomas, Daniel, Powell, Jason A., Green, Benjamin D., Barry, Emma F., Ma, Yuefang, Woodcock, Joanna, Fitter, Stephen, Zannettino, Andrew C. W., Pitson, Stuart M., Hughes, Timothy P., Lopez, Angel F., Shepherd, Peter R., Wei, Andrew H., Ekert, Paul G., Guthridge, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601961/
https://ncbi.nlm.nih.gov/pubmed/23526884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001515
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky