Characterisation of Peptide Microarrays for Studying Antibody-Antigen Binding Using Surface Plasmon Resonance Imagery

door Nogues, Claude, Leh, Hervé, Langendorf, Christopher G., Law, Ruby H. P., Buckle, Ashley M., Buckle, Malcolm
Gepubliceerd in 2010

Contribution of Conserved Lysine Residues in the α(2)-Antiplasmin C Terminus to Plasmin Binding and Inhibition

door Lu, Bernadine G. C., Sofian, Trifina, Law, Ruby H. P., Coughlin, Paul B., Horvath, Anita J.
Gepubliceerd in 2011

The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module

door Linke, Christian, Siemens, Nikolai, Oehmcke, Sonja, Radjainia, Mazdak, Law, Ruby H. P., Whisstock, James C., Baker, Edward N., Kreikemeyer, Bernd
Gepubliceerd in 2012

Prodepth: Predict Residue Depth by Support Vector Regression Approach from Protein Sequences Only

door Song, Jiangning, Tan, Hao, Mahmood, Khalid, Law, Ruby H. P., Buckle, Ashley M., Webb, Geoffrey I., Akutsu, Tatsuya, Whisstock, James C.
Gepubliceerd in 2009

Reconciling the Structural Attributes of Avian Antibodies

door Conroy, Paul J., Law, Ruby H. P., Gilgunn, Sarah, Hearty, Stephen, Caradoc-Davies, Tom T., Lloyd, Gordon, O'Kennedy, Richard J., Whisstock, James C.
Gepubliceerd in 2014

Structural Basis for Ca(2+)-mediated Interaction of the Perforin C2 Domain with Lipid Membranes

door Yagi, Hiromasa, Conroy, Paul J., Leung, Eleanor W. W., Law, Ruby H. P., Trapani, Joseph A., Voskoboinik, Ilia, Whisstock, James C., Norton, Raymond S.
Gepubliceerd in J Biol Chem (2015)

Cloning and Expression of the Major Secreted Cathepsin B-Like Protein from Juvenile Fasciola hepatica and Analysis of Immunogenicity following Liver Fluke Infection

door Law, Ruby H. P., Smooker, Peter M., Irving, James A., Piedrafita, David, Ponting, Rebecca, Kennedy, Nicholas J., Whisstock, James C., Pike, Robert N., Spithill, Terry W.
Gepubliceerd in 2003

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

door Voon, Hsiao P. J., Udugama, Maheshi, Lin, Wendi, Hii, Linda, Law, Ruby H.P., Steer, David L., Das, Partha P., Mann, Jeffrey R., Wong, Lee H.
Gepubliceerd in Nat Commun (2018)

The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP(+)/Enzyme Interactions

door Langendorf, Christopher G., Key, Trevor L. G., Fenalti, Gustavo, Kan, Wan-Ting, Buckle, Ashley M., Caradoc-Davies, Tom, Tuck, Kellie L., Law, Ruby H. P., Whisstock, James C.
Gepubliceerd in 2010

Maspin is not required for embryonic development or tumour suppression

door Teoh, Sonia S. Y., Vieusseux, Jessica, Prakash, Monica, Berkowicz, Susan, Luu, Jennii, Bird, Catherina H., Law, Ruby H. P., Rosado, Carlos, Price, John T., Whisstock, James C., Bird, Phillip I.
Gepubliceerd in 2014

Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin

door Brennan, Amelia J., Law, Ruby H. P., Conroy, Paul J., Noori, Tahereh, Lukoyanova, Natalya, Saibil, Helen, Yagita, Hideo, Ciccone, Annette, Verschoor, Sandra, Whisstock, James C., Trapani, Joseph A., Voskoboinik, Ilia
Gepubliceerd in Cell Death Differ (2018)

Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes

door Yuan, Yue, Ayinuola, Yetunde A., Singh, Damini, Ayinuola, Olawole, Mayfield, Jeffrey A., Quek, Adam, Whisstock, James C., Law, Ruby H.P., Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Gepubliceerd in J Struct Biol (2019)

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

door Langendorf, Christopher G., Tuck, Kellie L., Key, Trevor L. G., Fenalti, Gustavo, Pike, Robert N., Rosado, Carlos J., Wong, Anders S. M., Buckle, Ashley M., Law, Ruby H. P., Whisstock, James C.
Gepubliceerd in 2013

The MACPF/CDC family of pore-forming toxins

door Rosado, Carlos J, Kondos, Stephanie, Bull, Tara E, Kuiper, Michael J, Law, Ruby H P, Buckle, Ashley M, Voskoboinik, Ilia, Bird, Phillip I, Trapani, Joseph A, Whisstock, James C, Dunstone, Michelle A
Gepubliceerd in 2008

Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase

door Cork, Amanda J., Ericsson, Daniel J., Law, Ruby H. P., Casey, Lachlan W., Valkov, Eugene, Bertozzi, Carlo, Stamp, Anna, Jovcevski, Blagojce, Aquilina, J. Andrew, Whisstock, James C., Walker, Mark J., Kobe, Bostjan
Gepubliceerd in PLoS One (2015)

X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors

door Law, Ruby H. P., Wu, Guojie, Leung, Eleanor W. W., Hidaka, Koushi, Quek, Adam J., Caradoc-Davies, Tom T., Jeevarajah, Devadharshini, Conroy, Paul J., Kirby, Nigel M., Norton, Raymond S., Tsuda, Yuko, Whisstock, James C.
Gepubliceerd in Blood Adv (2017)

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

door Wu, Guojie, Mazzitelli, Blake A., Quek, Adam J., Veldman, Matthew J., Conroy, Paul J., Caradoc-Davies, Tom T., Ooms, Lisa M., Tuck, Kellie L., Schoenecker, Jonathan G., Whisstock, James C., Law, Ruby H. P.
Gepubliceerd in Blood Adv (2019)

The N terminus of the serpin, tengpin, functions to trap the metastable native state

door Zhang, Qingwei, Buckle, Ashley M, Law, Ruby H P, Pearce, Mary C, Cabrita, Lisa D, Lloyd, Gordon J, Irving, James A, Smith, A Ian, Ruzyla, Katya, Rossjohn, Jamie, Bottomley, Stephen P, Whisstock, James C
Gepubliceerd in 2007

X-ray crystal structure of the streptococcal specific phage lysin PlyC

door McGowan, Sheena, Buckle, Ashley M., Mitchell, Michael S., Hoopes, James T., Gallagher, D. Travis, Heselpoth, Ryan D., Shen, Yang, Reboul, Cyril F., Law, Ruby H. P., Fischetti, Vincent A., Whisstock, James C., Nelson, Daniel C.
Gepubliceerd in 2012

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

door Kaiserman, Dion, Buckle, Ashley M., Van Damme, Petra, Irving, James A., Law, Ruby H. P., Matthews, Antony Y., Bashtannyk-Puhalovich, Tanya, Langendorf, Chris, Thompson, Philip, Vandekerckhove, Joël, Gevaert, Kris, Whisstock, James C., Bird, Phillip I.
Gepubliceerd in 2009