Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes

VEK50 is a truncated peptide from a Streptococcal pyogenes surface human plasminogen (hPg) binding M-protein (PAM). VEK50 contains the full A-domain of PAM, which is responsible for its low nanomolar binding to hPg. The interaction of VEK50 with kringle 2, the PAM-binding domain in hPg (K2(hPg)), ha...

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Bibliographic Details
Published in:J Struct Biol
Main Authors: Yuan, Yue, Ayinuola, Yetunde A., Singh, Damini, Ayinuola, Olawole, Mayfield, Jeffrey A., Quek, Adam, Whisstock, James C., Law, Ruby H.P., Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983471/
https://ncbi.nlm.nih.gov/pubmed/31301349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.07.005
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