Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization

Group A Streptococcus pyogenes (GAS) is a causative agent of pharyngeal and dermal infections in humans. A major virulence determinant of GAS is its dimeric signature fibrillar M-protein (M-Prt), which is evolutionarily designed in modules, ranging from a hypervariable extracellular N-terminal regio...

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Publicado no:J Struct Biol
Main Authors: Qiu, Cunjia, Yuan, Yue, Zajicek, Jaroslav, Liang, Zhong, Balsara, Rashna D., Brito-Robionson, Teresa, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544907/
https://ncbi.nlm.nih.gov/pubmed/30071314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2018.07.017
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