Complement-mediated Opsonization of Invasive Group A Streptococcus pyogenes Strain AP53 Is Regulated by the Bacterial Two-component Cluster of Virulence Responder/Sensor (CovRS) System

Group A Streptococcus pyogenes (GAS) strain AP53 is a primary isolate from a patient with necrotizing fasciitis. These AP53 cells contain an inactivating mutation in the sensor component of the cluster of virulence (cov) responder (R)/sensor (S) two-component gene regulatory system (covRS), which en...

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Détails bibliographiques
Auteurs principaux: Agrahari, Garima, Liang, Zhong, Mayfield, Jeffrey A., Balsara, Rashna D., Ploplis, Victoria A., Castellino, Francis J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779743/
https://ncbi.nlm.nih.gov/pubmed/23928307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494864
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