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CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus pyogenes Provides New Insights into Virulence Determinants

The two-component control of virulence (Cov) regulator (R)-sensor (S) (CovRS) regulates the virulence of Streptococcus pyogenes (group A Streptococcus [GAS]). Inactivation of CovS during infection switches the pathogenicity of GAS to a more invasive form by regulating transcription of diverse virule...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Bao, Yun-Juan, Liang, Zhong, Mayfield, Jeffrey A., Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560280/
https://ncbi.nlm.nih.gov/pubmed/26216843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00511-15
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