Variations in the secondary structures of PAM proteins influence their binding affinities to human plasminogen

M-proteins (M-Prts) are major virulence determinants of Group A Streptococcus pyogenes (GAS) that are covalently anchored to the cell wall at their conserved COOH-termini while the NH(2)-terminal regions extend through the capsule into extracellular space. Functional M-Prts are also secreted and/or...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Struct Biol
Main Authors: Qiu, Cunjia, Yuan, Yue, Liang, Zhong, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502667/
https://ncbi.nlm.nih.gov/pubmed/30880082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.03.003
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