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X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors
The zymogen protease plasminogen and its active form plasmin perform key roles in blood clot dissolution, tissue remodeling, cell migration, and bacterial pathogenesis. Dysregulation of the plasminogen/plasmin system results in life-threatening hemorrhagic disorders or thrombotic vascular occlusion....
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| Publicado no: | Blood Adv |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728053/ https://ncbi.nlm.nih.gov/pubmed/29296720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016004150 |
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