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Cloning and Expression of the Major Secreted Cathepsin B-Like Protein from Juvenile Fasciola hepatica and Analysis of Immunogenicity following Liver Fluke Infection

The functions of the cathepsin B-like proteases in liver flukes are unknown and analysis has been hindered by a lack of protein for study, since the protein is produced in small amounts by juvenile flukes. To circumvent this, we isolated and characterized a cDNA encoding the major secreted cathepsin...

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Główni autorzy: Law, Ruby H. P., Smooker, Peter M., Irving, James A., Piedrafita, David, Ponting, Rebecca, Kennedy, Nicholas J., Whisstock, James C., Pike, Robert N., Spithill, Terry W.
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2003
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC308908/
https://ncbi.nlm.nih.gov/pubmed/14638781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.6921-6932.2003
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