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X-ray crystal structure of the streptococcal specific phage lysin PlyC

Bacteriophages deploy lysins that degrade the bacterial cell wall and facilitate virus egress from the host. When applied exogenously, these enzymes destroy susceptible microbes and, accordingly, have potential as therapeutic agents. The most potent lysin identified to date is PlyC, an enzyme assemb...

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Detalhes bibliográficos
Main Authors: McGowan, Sheena, Buckle, Ashley M., Mitchell, Michael S., Hoopes, James T., Gallagher, D. Travis, Heselpoth, Ryan D., Shen, Yang, Reboul, Cyril F., Law, Ruby H. P., Fischetti, Vincent A., Whisstock, James C., Nelson, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412044/
https://ncbi.nlm.nih.gov/pubmed/22807482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208424109
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