X-ray crystal structure of the streptococcal specific phage lysin PlyC

Bacteriophages deploy lysins that degrade the bacterial cell wall and facilitate virus egress from the host. When applied exogenously, these enzymes destroy susceptible microbes and, accordingly, have potential as therapeutic agents. The most potent lysin identified to date is PlyC, an enzyme assemb...

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Main Authors: McGowan, Sheena, Buckle, Ashley M., Mitchell, Michael S., Hoopes, James T., Gallagher, D. Travis, Heselpoth, Ryan D., Shen, Yang, Reboul, Cyril F., Law, Ruby H. P., Fischetti, Vincent A., Whisstock, James C., Nelson, Daniel C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412044/
https://ncbi.nlm.nih.gov/pubmed/22807482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208424109
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