The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP(+)/Enzyme Interactions

BACKGROUND: In mammals succinic semialdehyde dehydrogenase (SSADH) plays an essential role in the metabolism of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) to succinic acid (SA). Deficiency of SSADH in humans results in elevated levels of GABA and γ-Hydroxybutyric acid (GHB), which le...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Langendorf, Christopher G., Key, Trevor L. G., Fenalti, Gustavo, Kan, Wan-Ting, Buckle, Ashley M., Caradoc-Davies, Tom, Tuck, Kellie L., Law, Ruby H. P., Whisstock, James C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823781/
https://ncbi.nlm.nih.gov/pubmed/20174634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009280
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki