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Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases
Class I phosphoinositide 3-kinase (PI3K) generates phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) at the plasma membrane in response to growth factors, activating a signalling cascade that regulates many cellular functions including cell growth, proliferation, survival, migration and m...
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Publicado no: | Biosci Rep |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301276/ https://ncbi.nlm.nih.gov/pubmed/28082369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160432 |
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