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Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases
Class I phosphoinositide 3-kinase (PI3K) generates phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) at the plasma membrane in response to growth factors, activating a signalling cascade that regulates many cellular functions including cell growth, proliferation, survival, migration and m...
Guardat en:
| Publicat a: | Biosci Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301276/ https://ncbi.nlm.nih.gov/pubmed/28082369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160432 |
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