CBP Is a Dosage-Dependent Regulator of Nuclear Factor-κB Suppression by the Estrogen Receptor

由 Nettles, Kendall W., Gil, German, Nowak, Jason, Métivier, Raphaël, Sharma, Vandana B., Greene, Geoffrey L.
出版 2008

Ligand-binding dynamics rewire cellular signaling via Estrogen Receptor-α

由 Srinivasan, Sathish, Nwachukwu, Jerome C., Parent, Alex A., Cavett, Valerie, Nowak, Jason, Hughes, Travis S., Kojetin, Douglas J., Katzenellenbogen, John A., Nettles, Kendall W.
出版 2013

Coupling of Receptor Conformation and Ligand Orientation Determine Graded Activity

由 Bruning, John B., Parent, Alex A., Gil, German, Zhao, Min, Nowak, Jason, Pace, Margaret C., Smith, Carolyn L., Afonine, Pavel V., Adams, Paul D., Katzenellenbogen, John A., Nettles, Kendall W.
出版 2010

Structural plasticity in the oestrogen receptor ligand-binding domain

由 Nettles, Kendall W, Bruning, John B, Gil, German, O'Neill, Erin E, Nowak, Jason, Guo, Yuee, Kim, Younchang, DeSombre, Eugene R, Dilis, Robert, Hanson, Robert N, Joachimiak, Andrzej, Greene, Geoffrey L
出版 2007

Structural plasticity in the oestrogen receptor ligand-binding domain

由 Nettles, Kendall W, Bruning, John B, Gil, German, O'Neill, Erin E, Nowak, Jason, Hughs, Alun, Kim, Younchang, DeSombre, Eugene R, Dilis, Robert, Hanson, Robert N, Joachimiak, Andrzej, Greene, Geoffrey L
出版 2007

NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

由 Nettles, Kendall W., Bruning, John B., Gil, German, Nowak, Jason, Sharma, Sanjay K., Hahm, Johnnie B., Kulp, Kristen, Hochberg, Richard B., Zhou, Haibing, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Kim, Younchang, Joachmiak, Andrzej, Greene, Geoffrey L.
出版 2008

Predictive features of ligand‐specific signaling through the estrogen receptor

由 Nwachukwu, Jerome C, Srinivasan, Sathish, Zheng, Yangfan, Wang, Song, Min, Jian, Dong, Chune, Liao, Zongquan, Nowak, Jason, Wright, Nicholas J, Houtman, René, Carlson, Kathryn E, Josan, Jatinder S, Elemento, Olivier, Katzenellenbogen, John A, Zhou, Hai‐Bing, Nettles, Kendall W
發表在 Mol Syst Biol (2016)

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

由 Kojetin, Douglas J., Matta-Camacho, Edna, Hughes, Travis S., Srinivasan, Sathish, Nwachukwu, Jerome C., Cavett, Valerie, Nowak, Jason, Chalmers, Michael J., Marciano, David P., Kamenecka, Theodore M., Shulman, Andrew I., Rance, Mark, Griffin, Patrick R., Bruning, John B., Nettles, Kendall W.
發表在 Nat Commun (2015)

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

由 Nwachukwu, Jerome C, Srinivasan, Sathish, Bruno, Nelson E, Parent, Alexander A, Hughes, Travis S, Pollock, Julie A, Gjyshi, Olsi, Cavett, Valerie, Nowak, Jason, Garcia-Ordonez, Ruben D, Houtman, René, Griffin, Patrick R, Kojetin, Douglas J, Katzenellenbogen, John A, Conkright, Michael D, Nettles, Kendall W
出版 2014

Full Antagonism of the Estrogen Receptor without a Prototypical Ligand Side Chain

由 Srinivasan, Sathish, Nwachukwu, Jerome C., Bruno, Nelson E., Dharmarajan, Venkatasubramanian, Goswami, Devrishi, Kastrati, Irida, Novick, Scott, Nowak, Jason, Cavett, Valerie, Zhou, Hai-Bing, Boonmuen, Nittaya, Zhao, Yuechao, Min, Jian, Frasor, Jonna, Katzenellenbogen, Benita S., Griffin, Patrick R., Katzenellenbogen, John A., Nettles, Kendall W.
發表在 Nat Chem Biol (2016)

Structural and molecular mechanisms of cytokine-mediated endocrine resistance in human breast cancer cells

由 Stender, Joshua D., Nwachukwu, Jerome C., Kastrati, Irida, Kim, Yohan, Strid, Tobias, Yakir, Maayan, Srinivasan, Sathish, Nowak, Jason, Izard, Tina, Erumbi, Rangarajan, Carlson, Kathryn E., Katzenellenbogen, John A., Yao, Xin-Qiu, Grant, Barry J., Leong, Hon S, Lin, Chin-Yo, Frasor, Jonna, Nettles, Kendall W., Glass, Christopher K.
發表在 Mol Cell (2017)

Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat

由 Mediouni, Sonia, Chinthalapudi, Krishna, Ekka, Mary K., Usui, Ippei, Jablonski, Joseph A., Clementz, Mark A., Mousseau, Guillaume, Nowak, Jason, Macherla, Venkat R., Beverage, Jacob N., Esquenazi, Eduardo, Baran, Phil, de Vera, Ian Mitchelle S., Kojetin, Douglas, Loret, Erwann P., Nettles, Kendall, Maiti, Souvik, Izard, Tina, Valente, Susana T.
發表在 mBio (2019)

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

由 Fanning, Sean W, Jeselsohn, Rinath, Dharmarajan, Venkatasubramanian, Mayne, Christopher G, Karimi, Mostafa, Buchwalter, Gilles, Houtman, René, Toy, Weiyi, Fowler, Colin E, Han, Ross, Lainé, Muriel, Carlson, Kathryn E, Martin, Teresa A, Nowak, Jason, Nwachukwu, Jerome C, Hosfield, David J, Chandarlapaty, Sarat, Tajkhorshid, Emad, Nettles, Kendall W, Griffin, Patrick R, Shen, Yang, Katzenellenbogen, John A, Brown, Myles, Greene, Geoffrey L
發表在 eLife (2018)