NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

Understanding how steroid hormones regulate physiological functions has been significantly advanced by structural biology approaches. However, progress has been hampered by significant misfolding of the ligand binding domains in heterologous expression systems and by conformational flexibility that...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Nettles, Kendall W., Bruning, John B., Gil, German, Nowak, Jason, Sharma, Sanjay K., Hahm, Johnnie B., Kulp, Kristen, Hochberg, Richard B., Zhou, Haibing, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Kim, Younchang, Joachmiak, Andrzej, Greene, Geoffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659626/
https://ncbi.nlm.nih.gov/pubmed/18344977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.76
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi