NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

Understanding how steroid hormones regulate physiological functions has been significantly advanced by structural biology approaches. However, progress has been hampered by significant misfolding of the ligand binding domains in heterologous expression systems and by conformational flexibility that...

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Библиографические подробности
Главные авторы: Nettles, Kendall W., Bruning, John B., Gil, German, Nowak, Jason, Sharma, Sanjay K., Hahm, Johnnie B., Kulp, Kristen, Hochberg, Richard B., Zhou, Haibing, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Kim, Younchang, Joachmiak, Andrzej, Greene, Geoffrey L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659626/
https://ncbi.nlm.nih.gov/pubmed/18344977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.76
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