NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

Understanding how steroid hormones regulate physiological functions has been significantly advanced by structural biology approaches. However, progress has been hampered by significant misfolding of the ligand binding domains in heterologous expression systems and by conformational flexibility that...

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Detaylı Bibliyografya
Asıl Yazarlar: Nettles, Kendall W., Bruning, John B., Gil, German, Nowak, Jason, Sharma, Sanjay K., Hahm, Johnnie B., Kulp, Kristen, Hochberg, Richard B., Zhou, Haibing, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Kim, Younchang, Joachmiak, Andrzej, Greene, Geoffrey L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659626/
https://ncbi.nlm.nih.gov/pubmed/18344977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.76
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