Rational design and optimization of selenophenes with basic side chains as novel potent selective estrogen receptor modulators (SERMs) for breast cancer therapy

Por Luo, Junjie, Hu, Zhiye, Xiao, Yuan, Yang, Tongxin, Dong, Chune, Huang, Jian, Zhou, Hai-Bing
Publicado no Medchemcomm (2017)

Selenophenes: Introducing a New Element into the Core of Non-Steroidal Estrogen Receptor Ligands

Por Zhang, Silong, Wang, Zhiyong, Hu, Zhiye, Li, Changhao, Tang, Chu, Carlson, Kathryn E., Luo, Junjie, Dong, Chune, Katzenellenbogen, John A., Huang, Jian, Zhou, Hai-Bing
Publicado no ChemMedChem (2017)

Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure–activity relationships of estrogen receptor ligands based on bridged oxabicyclic core ar...

Por Zhu, Manghong, Zhang, Chen, Nwachukwu, Jerome C., Srinivasan, Sathish, Cavett, Valerie, Zheng, Yangfan, Carlson, Kathryn E., Dong, Chune, Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing
Publicado em 2012

Triaryl-Substituted Schiff Bases Are High-Affinity Subtype-Selective Ligands for the Estrogen Receptor

Por Liao, Zong-Quan, Dong, Chune, Carlson, Kathryn E., Srinivasan, Sathish, Nwachukwu, Jerome C., Chesnut, Robert W., Sharma, Abhishek, Nettles, Kendall W., Katzenellenbogen, John A., Zhou, Hai-Bing
Publicado em 2014

Identification and Structure-Activity Relationships of a Novel Series of Estrogen Receptor Ligands Based on 7-Thiabicyclo[2.2.1]hept-2-ene-7-oxide()

Por Wang, Pengcheng, Min, Jian, Nwachukwu, Jerome C., Cavett, Valerie, Carlson, Kathryn E., Guo, Pu, Zhu, Manghong, Zheng, Yangfan, Dong, Chune, Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing
Publicado em 2012

Development of Selective Estrogen Receptor Modulator (SERM)-Like Activity Through an Indirect Mechanism of Estrogen Receptor Antagonism: Defining the Binding Mode of 7-Oxabicyclo[2...

Por Zheng, Yangfan, Zhu, Manghong, Srinivasan, Sathish, Nwachukwu, Jerome C., Cavett, Valerie, Min, Jian, Carlson, Kathryn E., Wang, Pengcheng, Dong, Chune, Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing
Publicado no ChemMedChem (2012)

Predictive features of ligand‐specific signaling through the estrogen receptor

Por Nwachukwu, Jerome C, Srinivasan, Sathish, Zheng, Yangfan, Wang, Song, Min, Jian, Dong, Chune, Liao, Zongquan, Nowak, Jason, Wright, Nicholas J, Houtman, René, Carlson, Kathryn E, Josan, Jatinder S, Elemento, Olivier, Katzenellenbogen, John A, Zhou, Hai‐Bing, Nettles, Kendall W
Publicado no Mol Syst Biol (2016)