Steroidal Bivalent Ligands for the Estrogen Receptor: Design, Synthesis, Characterization and Binding Affinities

Por LaFrate, Andrew L., Carlson, Kathryn E., Katzenellenbogen, John A.
Publicado em 2009

Exploration of Dimensions of Estrogen Potency: PARSING LIGAND BINDING AND COACTIVATOR BINDING AFFINITIES

Por Jeyakumar, M., Carlson, Kathryn E., Gunther, Jillian R., Katzenellenbogen, John A.
Publicado em 2011

Diarylpropionitrile (DPN) Enantiomers: Synthesis and Evaluation of Estrogen Receptor Beta-Selective Ligands

Por Carroll, Vincent M., Jeyakumar, M., Carlson, Kathryn E., Katzenellenbogen, John A.
Publicado em 2011

Synthesis and Biological Evaluation of Guanylhydrazone Coactivator Binding Inhibitors for the Estrogen Receptor

Por LaFrate, Andrew L., Gunther, Jillian R., Carlson, Kathryn E., Katzenellenbogen, John A.
Publicado em 2008

Analogs of Methyl-Piperidinopyrazole (MPP): Antiestrogens with Estrogen Receptor α Selective Activity

Por Zhou, Hai-Bing, Carlson, Kathryn E., Stossi, Fabio, Katzenellenbogen, Benita S., Katzenellenbogen, John A.
Publicado em 2008

Characterization of the Pharmacophore Properties of Novel Selective Estrogen Receptor Downregulators (SERDs)

Por Kieser, Karen J., Kim, Dong Wook, Carlson, Kathryn E., Katzenellenbogen, Benita S., Katzenellenbogen, John A.
Publicado em 2010

Imaging progesterone receptor in breast tumors: Synthesis and receptor binding affinity of fluoroalkyl-substituted analogs of Tanaproget

Por Zhou, Hai-Bing, Lee, Jae Hak, Mayne, Christopher G., Carlson, Kathryn E., Katzenellenbogen, John A.
Publicado em 2010

Phenethyl pyridines with non-polar internal substitutents as selective ligands for estrogen receptor beta

Por Waibel, Michael, Kieser, Karen J., Carlson, Kathryn E., Stossi, Fabio, Katzenellenbogen, Benita S., Katzenellenbogen, John A.
Publicado em 2009

Fluorine-Substituted Cyclofenil Derivatives as Estrogen Receptor Ligands: Synthesis and Structure-Affinity Relationship Study of Potential PET Agents for Imaging Estrogen Receptors...

Por Seo, Jai Woong, Comninos, John S., Chi, Dae Yoon, Kim, Dong Wook, Carlson, Kathryn E., Katzenellenbogen, John A.
Publicado em 2006

Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta

Por Waibel, Michael, De Angelis, Meri, Stossi, Fabio, Kieser, Karen J., Carlson, Kathryn E., Katzenellenbogen, Benita S., Katzenellenbogen, John A.
Publicado em 2009

Nonsteroidal Bivalent Estrogen Ligands - An Application of the Bivalent Concept to the Estrogen Receptor

Por Shan, Min, Carlson, Kathryn E., Bujotzek, Alexander, Wellner, Anja, Gust, Ronald, Weber, Marcus, Katzenellenbogen, John A., Haag, Rainer
Publicado em 2013

Exploring the Structural Compliancy vs. Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands

Por Sharma, Naina, Carlson, Kathryn E., Nwachukwu, Jerome C., Srinivasan, Sathish, Sharma, Abhishek, Nettles, Kendall W., Katzenellenbogen, John A.
Publicado no ACS Chem Biol (2016)

Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands

Por Durrant, Jacob D., Carlson, Kathryn E., Martin, Teresa A., Offutt, Tavina L., Mayne, Christopher G., Katzenellenbogen, John A., Amaro, Rommie E.
Publicado no J Chem Inf Model (2015)

Synthesis and receptor binding in trans-CD ring-fused A-CD estrogens: Comparison with the cis-fused isomers

Por Dabrota, Cristian, Asim, Muhammad, Choueiri, Christine, Gargaun, Ana, Korobkov, Ilya, Butt, Ammara, Carlson, Kathryn E., Katzenellenbogen, John A., Wright, James S., Durst, Tony
Publicado no Bioorg Med Chem Lett (2014)

Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History

Por Kim, Sung Hoon, Madak-Erdogan, Zeynep, Bae, Sung Chul, Carlson, Kathryn E., Mayne, Christopher G., Granick, Steve, Katzenellenbogen, Benita S., Katzenellenbogen, John A.
Publicado no J Am Chem Soc (2015)

Cyclic-ketoximes as ER beta-selective agonists

Por Granchi, Carlotta, Lapillo, Margherita, Spena, Concetta Russo, Rizzolio, Flavio, Tuccinardi, Tiziano, Martin, Teresa A., Carlson, Kathryn E., Katzenellenbogen, John A., Minutolo, Filippo
Publicado no ChemMedChem (2016)

Synthesis and Biological Evaluation of Two Agents for Imaging Estrogen Receptor β by Positron Emission Tomography: Challenges in PET Imaging of a Low Abundance Target

Por HakLee, Jae, Peters, Olaf, Lehmann, Lutz, Dence, Carmen S., Sharp, Terry L., Carlson, Kathryn E., Zhou, Dong, Jeyakumar, M., Welch, Michael J., Katzenellenbogen, John A.
Publicado em 2012

Thiophene-Core Estrogen Receptor Ligands Having Superagonist Activity

Por Min, Jian, Wang, Pengcheng, Srinivasan, Sathish, Nwachukwu, Jerome C., Guo, Pu, Huang, Minjian, Carlson, Kathryn E., Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing
Publicado em 2013

Selenophenes: Introducing a New Element into the Core of Non-Steroidal Estrogen Receptor Ligands

Por Zhang, Silong, Wang, Zhiyong, Hu, Zhiye, Li, Changhao, Tang, Chu, Carlson, Kathryn E., Luo, Junjie, Dong, Chune, Katzenellenbogen, John A., Huang, Jian, Zhou, Hai-Bing
Publicado no ChemMedChem (2017)

Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes

Por Bertini, Simone, De Cupertinis, Andrea, Granchi, Carlotta, Bargagli, Barbara, Tuccinardi, Tiziano, Martinelli, Adriano, Macchia, Marco, Gunther, Jillian R., Carlson, Kathryn E., Katzenellenbogen, John A., Minutolo, Filippo
Publicado em 2011