Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors

por Poli, Giulio, Jha, Vibhu, Martinelli, Adriano, Supuran, Claudiu T., Tuccinardi, Tiziano
Publicado no Int J Mol Sci (2018)

Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

por Poli, Giulio, Galati, Salvatore, Martinelli, Adriano, Supuran, Claudiu T., Tuccinardi, Tiziano
Publicado no J Enzyme Inhib Med Chem (2019)

Extensive Reliability Evaluation of Docking-Based Target-Fishing Strategies

por Lapillo, Margherita, Tuccinardi, Tiziano, Martinelli, Adriano, Macchia, Marco, Giordano, Antonio, Poli, Giulio
Publicado no Int J Mol Sci (2019)

Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

por Bassi, Gabriele, Favalli, Nicholas, Oehler, Sebastian, Martinelli, Adriano, Catalano, Marco, Scheuermann, Jörg, Neri, Dario
Publicado no Biochem Biophys Res Commun (2020)

Development and Validation of a Docking-Based Virtual Screening Platform for the Identification of New Lactate Dehydrogenase Inhibitors

por Granchi, Carlotta, Capecchi, Alice, Del Frate, Gianluca, Martinelli, Adriano, Macchia, Marco, Minutolo, Filippo, Tuccinardi, Tiziano
Publicado no Molecules (2015)

Phenylpropanoids and Flavonoids from Phlomis kurdica as Inhibitors of Human Lactate Dehydrogenase

por Bader, Ammar, Tuccinardi, Tiziano, Granchi, Carlotta, Martinelli, Adriano, Macchia, Marco, Minutolo, Filippo, De Tommasi, Nunziatina, Braca, Alessandra
Publicado no Phytochemistry (2015)

Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds

por Granchi, Carlotta, Calvaresi, Emilia C., Tuccinardi, Tiziano, Paterni, Ilaria, Macchia, Marco, Martinelli, Adriano, Hergenrother, Paul J., Minutolo, Filippo
Publicado em 2013

Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors

por Granchi, Carlotta, Caligiuri, Isabella, Bertelli, Eleonora, Poli, Giulio, Rizzolio, Flavio, Macchia, Marco, Martinelli, Adriano, Minutolo, Filippo, Tuccinardi, Tiziano
Publicado no J Enzyme Inhib Med Chem (2017)

Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes

por Bertini, Simone, De Cupertinis, Andrea, Granchi, Carlotta, Bargagli, Barbara, Tuccinardi, Tiziano, Martinelli, Adriano, Macchia, Marco, Gunther, Jillian R., Carlson, Kathryn E., Katzenellenbogen, John A., Minutolo, Filippo
Publicado em 2011

Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor

por Calvaresi, Emilia C., Granchi, Carlotta, Tuccinardi, Tiziano, Di Bussolo, Valeria, Huigens, Robert W., Lee, Hyang Yeon, Palchaudhuri, Rahul, Macchia, Marco, Martinelli, Adriano, Minutolo, Filippo, Hergenrother, Paul J.
Publicado em 2013

Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents

por Di Bussolo, Valeria, Calvaresi, Emilia C., Granchi, Carlotta, Del Bino, Linda, Frau, Ileana, Lang, Maria Chiara Dasso, Tuccinardi, Tiziano, Macchia, Marco, Martinelli, Adriano, Hergenrother, Paul J., Minutolo, Filippo
Publicado no RSC Adv (2015)

Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model

por Paterni, Ilaria, Bertini, Simone, Granchi, Carlotta, Tuccinardi, Tiziano, Macchia, Marco, Martinelli, Adriano, Caligiuri, Isabella, Toffoli, Giuseppe, Rizzolio, Flavio, Carlson, Kathryn E., Katzenellenbogen, Benita S., Katzenellenbogen, John A., Minutolo, Filippo
Publicado no J Med Chem (2015)

A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

por Bassi, Gabriele, Favalli, Nicholas, Vuk, Miriam, Catalano, Marco, Martinelli, Adriano, Trenner, Anika, Porro, Antonio, Yang, Su, Tham, Chuin Lean, Moroglu, Mustafa, Yue, Wyatt W., Conway, Stuart J., Vogt, Peter K., Sartori, Alessandro A., Scheuermann, Jörg, Neri, Dario
Publicado no Adv Sci (Weinh) (2020)