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Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors

Carbonic anhydrase II (CAII) is a zinc-containing metalloenzyme whose aberrant activity is associated with various diseases such as glaucoma, osteoporosis, and different types of tumors; therefore, the development of CAII inhibitors, which can represent promising therapeutic agents for the treatment...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Poli, Giulio, Jha, Vibhu, Martinelli, Adriano, Supuran, Claudiu T., Tuccinardi, Tiziano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073570/
https://ncbi.nlm.nih.gov/pubmed/29937490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071851
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