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Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII
A novel series of 8-substituted coumarin-based compounds, characterized by the presence of alkylpiperazine and arylpiperazine chains, were synthesized and tested for their inhibitory activity against four human carbonic anhydrase (hCA) isoforms. All compounds displayed nanomolar potency against the...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429297/ https://ncbi.nlm.nih.gov/pubmed/30857344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051208 |
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