Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors

[Image: see text] A small library of psoralen carboxylic acids and their corresponding benzenesulfonamide derivatives were designed and synthesized to evaluate their activity and selectivity toward tumor associated human carbonic anhydrase (hCA) isoforms IX and XII. Both psoralen acids and sulfonami...

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Opis bibliograficzny
Wydane w:ACS Med Chem Lett
Główni autorzy: Melis, Claudia, Distinto, Simona, Bianco, Giulia, Meleddu, Rita, Cottiglia, Filippo, Fois, Benedetta, Taverna, Domenico, Angius, Rossella, Alcaro, Stefano, Ortuso, Francesco, Gaspari, Marco, Angeli, Andrea, Del Prete, Sonia, Capasso, Clemente, Supuran, Claudiu T., Maccioni, Elias
Format: Artigo
Język:Inglês
Wydane: American Chemical Society 2018
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047168/
https://ncbi.nlm.nih.gov/pubmed/30034608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00170
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