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Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?

A set of compounds incorporating carbon-based zinc-binding groups (ZBGs), of the type PhX (X = COOH, CONH(2), CONHNH(2), CONHOH, CONHOMe), and the corresponding derivatives with sulphur(VI)-based ZBGs (X = SO(3)H, SO(2)NH(2), SO(2)NHNH(2), SO(2)NHOH, SO(2)NHOMe) were tested as inhibitors of all mamm...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Hovedforfatter: Supuran, Claudiu T.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009921/
https://ncbi.nlm.nih.gov/pubmed/29390912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1428572
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