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Coumarin carbonic anhydrase inhibitors from natural sources
Coumarins constitute a relatively new class of inhibitors of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), possessing a unique inhibition mechanism, acting as “prodrug inhibitors.” They undergo the hydrolysis of the lactone ring mediated by the esterase activity of CA. The formed 2-hydroxy-ci...
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| Publicado no: | J Enzyme Inhib Med Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470141/ https://ncbi.nlm.nih.gov/pubmed/32779543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1788009 |
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