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Experimental Carbonic Anhydrase Inhibitors for the Treatment of Hypoxic Tumors
Carbonic anhydrase (CA, EC 4.2.1.1) isoforms IX and XII are overexpressed in many hypoxic tumors as a consequence of the hypoxia inducible factor (HIF) activation cascade, being present in limited amounts in normal tissues. These enzymes together with many others are involved in the pH regulation an...
Tallennettuna:
| Julkaisussa: | J Exp Pharmacol |
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| Päätekijä: | |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Dove
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7751321/ https://ncbi.nlm.nih.gov/pubmed/33364855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JEP.S265620 |
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