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Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format
DNA-encoded chemical libraries (DEL) are increasingly being used for the discovery and optimization of small organic ligands to proteins of biological or pharmaceutical interest. The DNA fragments, that serve as amplifiable identification barcodes for individual compounds in the library, are typical...
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| Опубликовано в: : | Biochem Biophys Res Commun |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116422/ https://ncbi.nlm.nih.gov/pubmed/32386812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.04.035 |
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