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DNA-Encoded Chemical Libraries: Achievements and Remaining Challenges

DNA-encoded chemical libraries (DECLs) are collections of compounds, individually coupled to DNA tags serving as amplifiable identification barcodes. Since individual compounds can be identified by the associated DNA tag, they can be stored as a mixture, allowing the synthesis and screening of combi...

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Publicado en:FEBS Lett
Autores principales: Favalli, Nicholas, Bassi, Gabriele, Scheuermann, Jörg, Neri, Dario
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126621/
https://ncbi.nlm.nih.gov/pubmed/29683493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13068
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