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DNA-Encoded Chemical Libraries: Achievements and Remaining Challenges

DNA-encoded chemical libraries (DECLs) are collections of compounds, individually coupled to DNA tags serving as amplifiable identification barcodes. Since individual compounds can be identified by the associated DNA tag, they can be stored as a mixture, allowing the synthesis and screening of combi...

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Bibliografiske detaljer
Udgivet i:FEBS Lett
Main Authors: Favalli, Nicholas, Bassi, Gabriele, Scheuermann, Jörg, Neri, Dario
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126621/
https://ncbi.nlm.nih.gov/pubmed/29683493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13068
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