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DNA-Encoded Chemical Libraries: Achievements and Remaining Challenges

DNA-encoded chemical libraries (DECLs) are collections of compounds, individually coupled to DNA tags serving as amplifiable identification barcodes. Since individual compounds can be identified by the associated DNA tag, they can be stored as a mixture, allowing the synthesis and screening of combi...

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Publicat a:FEBS Lett
Autors principals: Favalli, Nicholas, Bassi, Gabriele, Scheuermann, Jörg, Neri, Dario
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126621/
https://ncbi.nlm.nih.gov/pubmed/29683493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13068
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