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Screening of copper and palladium-mediated reactions compatible with DNA-encoded chemical libraries

The construction of DNA-encoded chemical libraries (DECLs) crucially relies on the availability of chemical reactions, which are DNA-compatible and which exhibit high conversion rates for a large number of diverse substrates. In this work, we present our optimization and validation procedures for th...

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Detalhes bibliográficos
Publicado no:Helv Chim Acta
Main Authors: Favalli, Nicholas, Bassi, Gabriele, Zanetti, Tania, Scheuermann, Jörg, Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156289/
https://ncbi.nlm.nih.gov/pubmed/32292208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hlca.201900033
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