Selenophenes: Introducing a New Element into the Core of Non-Steroidal Estrogen Receptor Ligands

The importance of the heterocyclic core elements with peripheral phenolic and alkyl substituents as a dominant structural motif of ligands for estrogen receptor (ER) has been well recognized. Here, we expand the structural diversity of core elements by preparing selenium-containing heterocycles and...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Zhang, Silong, Wang, Zhiyong, Hu, Zhiye, Li, Changhao, Tang, Chu, Carlson, Kathryn E., Luo, Junjie, Dong, Chune, Katzenellenbogen, John A., Huang, Jian, Zhou, Hai-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405701/
https://ncbi.nlm.nih.gov/pubmed/27976818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600593
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