Control of Ion Selectivity in LeuT: Two Na(+) Binding Sites with two different mechanisms

Por Noskov, Sergei Y., Roux, Benoît
Publicado no J Mol Biol (2008)

Pendular proteins in gases and new avenues for characterization of macromolecules by ion mobility spectrometry

Por Shvartsburg, Alexandre A., Noskov, Sergei Y., Purves, Randy W., Smith, Richard D.
Publicado em 2009

The Structural Pathway for Water Permeation through Sodium-Glucose Cotransporters

Por Sasseville, Louis J., Cuervo, Javier E., Lapointe, Jean-Yves, Noskov, Sergei Y.
Publicado em 2011

Rehabilitating drug-induced long-QT promoters: In-silico design of hERG-neutral cisapride analogues with retained pharmacological activity

Por Durdagi, Serdar, Randall, Trevor, Duff, Henry J, Chamberlin, Adam, Noskov, Sergei Y
Publicado em 2014

Mapping the gating and permeation pathways in the voltage-gated proton channel Hv1

Por Chamberlin, Adam, Qiu, Feng, Wang, Yibo, Noskov, Sergei Y., Larsson, H. Peter
Publicado no J Mol Biol (2014)

Molecular Simulations of Solved Co-crystallized X-Ray Structures Identify Action Mechanisms of PDEδ Inhibitors

Por Salmas, Ramin Ekhteiari, Mestanoglu, Mert, Yurtsever, Mine, Noskov, Sergei Y., Durdagi, Serdar
Publicado no Biophys J (2015)

K(+) Block Is the Mechanism of Functional Asymmetry in Bacterial Na(v) Channels

Por Ngo, Van, Wang, Yibo, Haas, Stephan, Noskov, Sergei Y., Farley, Robert A.
Publicado no PLoS Comput Biol (2016)

Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS)

Por Concilio, Susanna C., Zhekova, Hristina R., Noskov, Sergei Y., Russell, Stephen J.
Publicado no PLoS One (2020)

Hydrophobic plug functions as a gate in voltage-gated proton channels

Por Chamberlin, Adam, Qiu, Feng, Rebolledo, Santiago, Wang, Yibo, Noskov, Sergei Y., Larsson, H. Peter
Publicado em 2014

Mapping Ryanodine Binding Sites in the Pore Cavity of Ryanodine Receptors

Por Ngo, Van A., Perissinotti, Laura L., Miranda, Williams, Chen, S. R. Wayne, Noskov, Sergei Y.
Publicado no Biophys J (2017)

Digging into Lipid Membrane Permeation for Cardiac Ion Channel Blocker d-Sotalol with All-Atom Simulations

Por DeMarco, Kevin R., Bekker, Slava, Clancy, Colleen E., Noskov, Sergei Y., Vorobyov, Igor
Publicado no Front Pharmacol (2018)

Refinement of a cryo-EM structure of hERG: Bridging structure and function

Por Khan, Hanif M., Guo, Jiqing, Duff, Henry J., Tieleman, D. Peter, Noskov, Sergei Y.
Publicado no Biophys J (2021)

Ion selectivity in channels and transporters

Por Roux, Benoît, Bernèche, Simon, Egwolf, Bernhard, Lev, Bogdan, Noskov, Sergei Y., Rowley, Christopher N., Yu, Haibo
Publicado em 2011

4-(4-(Dimethylamino)phenyl)-1-methylpyridinium (APP(+)) Is a Fluorescent Substrate for the Human Serotonin Transporter

Por Solis, Ernesto, Zdravkovic, Igor, Tomlinson, Ian D., Noskov, Sergei Y., Rosenthal, Sandra J., De Felice, Louis J.
Publicado em 2012

Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy

Por Finol-Urdaneta, Rocio K., Wang, Yibo, Al-Sabi, Ahmed, Zhao, Chunfeng, Noskov, Sergei Y., French, Robert J.
Publicado em 2014

Interactions of H562 in the S5 Helix with T618 and S621 in the Pore Helix Are Important Determinants of hERG1 Potassium Channel Structure and Function

Por Lees-Miller, James P., Subbotina, Julia O., Guo, Jiqing, Yarov-Yarovoy, Vladimir, Noskov, Sergei Y., Duff, Henry J.
Publicado em 2009

Kinetic Model for NS1643 Drug Activation of WT and L529I Variants of Kv11.1 (hERG1) Potassium Channel

Por Perissinotti, Laura L., Guo, Jiqing, De Biase, Pablo M., Clancy, Colleen E., Duff, Henry J., Noskov, Sergei Y.
Publicado no Biophys J (2015)

Acidification Asymmetrically Affects Voltage-dependent Anion Channel Implicating the Involvement of Salt Bridges

Por Teijido, Oscar, Rappaport, Shay M., Chamberlin, Adam, Noskov, Sergei Y., Aguilella, Vicente M., Rostovtseva, Tatiana K., Bezrukov, Sergey M.
Publicado em 2014

A Three-Dimensional Model of a Group II Intron RNA and Its Interaction with the Intron-Encoded Reverse Transcriptase

Por Dai, Lixin, Chai, Dinggeng, Gu, Shan-Qing, Gabel, Jesse, Noskov, Sergei Y., Blocker, Forrest J. H., Lambowitz, Alan M., Zimmerly, Steven
Publicado em 2008

Structure Driven Design of Novel Human Ether-A-Go-Go-Related-Gene Channel (hERG1) Activators

Por Guo, Jiqing, Durdagi, Serdar, Changalov, Mohamed, Perissinotti, Laura L., Hargreaves, Jason M., Back, Thomas G., Noskov, Sergei Y., Duff, Henry J.
Publicado em 2014