Effects of the donor acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction

Por Stojković, Vanja, Perissinotti, Laura L., Willmer, Daniel, Benkovic, Stephen J., Kohen, Amnon
Publicado no J Am Chem Soc (2012)

The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer

Por Stojković, Vanja, Perissinotti, Laura L., Lee, Jeeyeon, Benkovic, Stephen J., Kohen, Amnon
Publicado no Chem Commun (Camb) (2010)

Computational Membrane Biophysics: From Ion Channels Interactions with Drugs to Cellular Function

Por Miranda, Williams E., Ngo, Van A., Perissinotti, Laura L., Noskov, Sergei Yu.
Publicado no Biochim Biophys Acta (2017)

Mapping Ryanodine Binding Sites in the Pore Cavity of Ryanodine Receptors

Por Ngo, Van A., Perissinotti, Laura L., Miranda, Williams, Chen, S. R. Wayne, Noskov, Sergei Y.
Publicado no Biophys J (2017)

Folate binding site of flavin-dependent thymidylate synthase

Por Koehn, Eric M., Perissinotti, Laura L., Moghram, Salah, Prabhakar, Arjun, Lesley, Scott A., Mathews, Irimpan I., Kohen, Amnon
Publicado em 2012

Kinetic Model for NS1643 Drug Activation of WT and L529I Variants of Kv11.1 (hERG1) Potassium Channel

Por Perissinotti, Laura L., Guo, Jiqing, De Biase, Pablo M., Clancy, Colleen E., Duff, Henry J., Noskov, Sergei Y.
Publicado no Biophys J (2015)

Role of the pH in state-dependent blockade of hERG currents

Por Wang, Yibo, Guo, Jiqing, Perissinotti, Laura L., Lees-Miller, James, Teng, Guoqi, Durdagi, Serdar, Duff, Henry J., Noskov, Sergei Yu.
Publicado no Sci Rep (2016)

Structure Driven Design of Novel Human Ether-A-Go-Go-Related-Gene Channel (hERG1) Activators

Por Guo, Jiqing, Durdagi, Serdar, Changalov, Mohamed, Perissinotti, Laura L., Hargreaves, Jason M., Back, Thomas G., Noskov, Sergei Y., Duff, Henry J.
Publicado em 2014

Thiol redox biochemistry: insights from computer simulations

Por Zeida, Ari, Guardia, Carlos M., Lichtig, Pablo, Perissinotti, Laura L., Defelipe, Lucas A., Turjanski, Adrián, Radi, Rafael, Trujillo, Madia, Estrin, Darío A.
Publicado no Biophys Rev (2014)

Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study

Por Perissinotti, Laura L., De Biase, Pablo M., Guo, Jiqing, Yang, Pei-Chi, Lee, Miranda C., Clancy, Colleen E., Duff, Henry J., Noskov, Sergei Y.
Publicado no Front Physiol (2018)

NS1643 Interacts around L529 of hERG to Alter Voltage Sensor Movement on the Path to Activation

Por Guo, Jiqing, Cheng, Yen May, Lees-Miller, James P., Perissinotti, Laura L., Claydon, Tom W., Hull, Christina M., Thouta, Samrat, Roach, Daniel E., Durdagi, Serdar, Noskov, Sergei Y., Duff, Henry J.
Publicado no Biophys J (2015)

A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal‐induced arrhythmias

Por Yang, Pei‐Chi, Perissinotti, Laura L., López‐Redondo, Fernando, Wang, Yibo, DeMarco, Kevin R., Jeng, Mao‐Tsuen, Vorobyov, Igor, Harvey, Robert D., Kurokawa, Junko, Noskov, Sergei Y., Clancy, Colleen E.
Publicado no J Physiol (2017)