Effects of the donor acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction

by Stojković, Vanja, Perissinotti, Laura L., Willmer, Daniel, Benkovic, Stephen J., Kohen, Amnon
Published in J Am Chem Soc (2012)

The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer

by Stojković, Vanja, Perissinotti, Laura L., Lee, Jeeyeon, Benkovic, Stephen J., Kohen, Amnon
Published in Chem Commun (Camb) (2010)

Computational Membrane Biophysics: From Ion Channels Interactions with Drugs to Cellular Function

by Miranda, Williams E., Ngo, Van A., Perissinotti, Laura L., Noskov, Sergei Yu.
Published in Biochim Biophys Acta (2017)

Mapping Ryanodine Binding Sites in the Pore Cavity of Ryanodine Receptors

by Ngo, Van A., Perissinotti, Laura L., Miranda, Williams, Chen, S. R. Wayne, Noskov, Sergei Y.
Published in Biophys J (2017)

Folate binding site of flavin-dependent thymidylate synthase

by Koehn, Eric M., Perissinotti, Laura L., Moghram, Salah, Prabhakar, Arjun, Lesley, Scott A., Mathews, Irimpan I., Kohen, Amnon
Published 2012

Kinetic Model for NS1643 Drug Activation of WT and L529I Variants of Kv11.1 (hERG1) Potassium Channel

by Perissinotti, Laura L., Guo, Jiqing, De Biase, Pablo M., Clancy, Colleen E., Duff, Henry J., Noskov, Sergei Y.
Published in Biophys J (2015)

Role of the pH in state-dependent blockade of hERG currents

by Wang, Yibo, Guo, Jiqing, Perissinotti, Laura L., Lees-Miller, James, Teng, Guoqi, Durdagi, Serdar, Duff, Henry J., Noskov, Sergei Yu.
Published in Sci Rep (2016)

Structure Driven Design of Novel Human Ether-A-Go-Go-Related-Gene Channel (hERG1) Activators

by Guo, Jiqing, Durdagi, Serdar, Changalov, Mohamed, Perissinotti, Laura L., Hargreaves, Jason M., Back, Thomas G., Noskov, Sergei Y., Duff, Henry J.
Published 2014

Thiol redox biochemistry: insights from computer simulations

by Zeida, Ari, Guardia, Carlos M., Lichtig, Pablo, Perissinotti, Laura L., Defelipe, Lucas A., Turjanski, Adrián, Radi, Rafael, Trujillo, Madia, Estrin, Darío A.
Published in Biophys Rev (2014)

Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study

by Perissinotti, Laura L., De Biase, Pablo M., Guo, Jiqing, Yang, Pei-Chi, Lee, Miranda C., Clancy, Colleen E., Duff, Henry J., Noskov, Sergei Y.
Published in Front Physiol (2018)

NS1643 Interacts around L529 of hERG to Alter Voltage Sensor Movement on the Path to Activation

by Guo, Jiqing, Cheng, Yen May, Lees-Miller, James P., Perissinotti, Laura L., Claydon, Tom W., Hull, Christina M., Thouta, Samrat, Roach, Daniel E., Durdagi, Serdar, Noskov, Sergei Y., Duff, Henry J.
Published in Biophys J (2015)

A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal‐induced arrhythmias

by Yang, Pei‐Chi, Perissinotti, Laura L., López‐Redondo, Fernando, Wang, Yibo, DeMarco, Kevin R., Jeng, Mao‐Tsuen, Vorobyov, Igor, Harvey, Robert D., Kurokawa, Junko, Noskov, Sergei Y., Clancy, Colleen E.
Published in J Physiol (2017)