Mapping Ryanodine Binding Sites in the Pore Cavity of Ryanodine Receptors

Ryanodine (Ryd) irreversibly targets ryanodine receptors (RyRs), a family of intracellular calcium release channels essential for many cellular processes ranging from muscle contraction to learning and memory. Little is known of the atomistic details about how Ryd binds to RyRs. In this study, we us...

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Udgivet i:Biophys J
Main Authors: Ngo, Van A., Perissinotti, Laura L., Miranda, Williams, Chen, S. R. Wayne, Noskov, Sergei Y.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2017
Fag:
Channels and Transporters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406381/
https://ncbi.nlm.nih.gov/pubmed/28445755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.014
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