Characterization of a Ligand Binding Site in the Human Transient Receptor Potential Ankyrin 1 Pore

The pharmacology and regulation of Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel activity is intricate due to the physiological function as an integrator of multiple chemical, mechanical, and temperature stimuli as well as differences in species pharmacology. In this study, we describe...

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Autors principals: Klement, Göran, Eisele, Lina, Malinowsky, David, Nolting, Andreas, Svensson, Mats, Terp, Gitte, Weigelt, Dirk, Dabrowski, Michael
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
Matèries:
Channels and Transporters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576529/
https://ncbi.nlm.nih.gov/pubmed/23442958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.008
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