N-type Inactivation Features of Kv4.2 Channel Gating

We examined whether the N-terminus of Kv4.2 A-type channels (4.2NT) possesses an autoinhibitory N-terminal peptide domain, which, similar to the one of Shaker, mediates inactivation of the open state. We found that chimeric Kv2.1(4.2NT) channels, where the cytoplasmic Kv2.1 N-terminus had been repla...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gebauer, Manuel, Isbrandt, Dirk, Sauter, Kathrin, Callsen, Britta, Nolting, Andreas, Pongs, Olaf, Bähring, Robert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2004
Pynciau:
Channels, Receptors, and Transporters
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303783/
https://ncbi.nlm.nih.gov/pubmed/14695263
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