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Intra- and Intersubunit Dynamic Binding in Kv4.2 Channel Closed-State Inactivation

We studied the kinetics and structural determinants of closed-state inactivation (CSI) in Kv4.2 channels, considering a multistep process and the possibility that both intra- and intersubunit dynamic binding (i.e., loss and restoration of physical contact) may occur between the S4-S5 linker, includi...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Wollberg, Jessica, Bähring, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805869/
https://ncbi.nlm.nih.gov/pubmed/26745419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.046
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