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Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation

Kv4 channels mediate the somatodendritic A-type K(+) current (I(SA)) in neurons. The availability of functional Kv4 channels is dynamically regulated by the membrane potential such that subthreshold depolarizations render Kv4 channels unavailable. The underlying process involves inactivation from cl...

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Sonraí Bibleagrafaíochta
Main Authors: Dougherty, Kevin, De Santiago-Castillo, Jose A., Covarrubias, Manuel
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248721/
https://ncbi.nlm.nih.gov/pubmed/18299396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709938
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