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Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation

Kv4 channels mediate the somatodendritic A-type K(+) current (I(SA)) in neurons. The availability of functional Kv4 channels is dynamically regulated by the membrane potential such that subthreshold depolarizations render Kv4 channels unavailable. The underlying process involves inactivation from cl...

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Detalhes bibliográficos
Main Authors: Dougherty, Kevin, De Santiago-Castillo, Jose A., Covarrubias, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248721/
https://ncbi.nlm.nih.gov/pubmed/18299396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709938
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