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Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K(+) channels in cerebellar granule neurons

Kv4 channels mediate most of the somatodendritic subthreshold operating A-type current (I(SA)) in neurons. This current plays essential roles in the regulation of spike timing, repetitive firing, dendritic integration and plasticity. Neuronal Kv4 channels are thought to be ternary complexes of Kv4 p...

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Autores principales: Amarillo, Yimy, De Santiago-Castillo, Jose A, Dougherty, Kevin, Maffie, Jonathon, Kwon, Elaine, Covarrubias, Manuel, Rudy, Bernardo
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465190/
https://ncbi.nlm.nih.gov/pubmed/18276729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.150540
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