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Mechanisms of closed-state inactivation in voltage-gated ion channels

Inactivation of voltage-gated ion channels is an intrinsic auto-regulatory process necessary to govern the occurrence and shape of action potentials and establish firing patterns in excitable tissues. Inactivation may occur from the open state (open-state inactivation, OSI) at strongly depolarized m...

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Détails bibliographiques
Auteurs principaux: Bähring, Robert, Covarrubias, Manuel
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055536/
https://ncbi.nlm.nih.gov/pubmed/21098008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191965
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