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The Tetramerization Domain Potentiates Kv4 Channel Function by Suppressing Closed-State Inactivation
A-type Kv4 potassium channels undergo a conformational change toward a nonconductive state at negative membrane potentials, a dynamic process known as pre-open closed states or closed-state inactivation (CSI). CSI causes inhibition of channel activity without the prerequisite of channel opening, thu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156681/ https://ncbi.nlm.nih.gov/pubmed/25185545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.038 |
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