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The Tetramerization Domain Potentiates Kv4 Channel Function by Suppressing Closed-State Inactivation

A-type Kv4 potassium channels undergo a conformational change toward a nonconductive state at negative membrane potentials, a dynamic process known as pre-open closed states or closed-state inactivation (CSI). CSI causes inhibition of channel activity without the prerequisite of channel opening, thu...

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Détails bibliographiques
Auteurs principaux: Tang, Yi-Quan, Zhou, Jing-Heng, Yang, Fan, Zheng, Jie, Wang, KeWei
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156681/
https://ncbi.nlm.nih.gov/pubmed/25185545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.038
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