Characterization of a Ligand Binding Site in the Human Transient Receptor Potential Ankyrin 1 Pore

The pharmacology and regulation of Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel activity is intricate due to the physiological function as an integrator of multiple chemical, mechanical, and temperature stimuli as well as differences in species pharmacology. In this study, we describe...

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Detalhes bibliográficos
Main Authors: Klement, Göran, Eisele, Lina, Malinowsky, David, Nolting, Andreas, Svensson, Mats, Terp, Gitte, Weigelt, Dirk, Dabrowski, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576529/
https://ncbi.nlm.nih.gov/pubmed/23442958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.008
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