Mapping Ryanodine Binding Sites in the Pore Cavity of Ryanodine Receptors

Ryanodine (Ryd) irreversibly targets ryanodine receptors (RyRs), a family of intracellular calcium release channels essential for many cellular processes ranging from muscle contraction to learning and memory. Little is known of the atomistic details about how Ryd binds to RyRs. In this study, we us...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Ngo, Van A., Perissinotti, Laura L., Miranda, Williams, Chen, S. R. Wayne, Noskov, Sergei Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406381/
https://ncbi.nlm.nih.gov/pubmed/28445755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.014
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