A carregar...

Changes in Negative Charge at the Luminal Mouth of the Pore Alter Ion Handling and Gating in the Cardiac Ryanodine-Receptor

We have tested the hypothesis that a high density of negative charge at the luminal mouth of the RyR2 pore plays a pivotal role in the high cation conductance and limited selectivity observed in this channel by introducing into each monomer a double point mutation to neutralize acidic residues in th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mead-Savery, Fiona C., Wang, Ruiwu, Tanna-Topan, Bhavna, Chen, S.R. Wayne, Welch, William, Williams, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717239/
https://ncbi.nlm.nih.gov/pubmed/19217855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.054
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!