Skeletal and Cardiac Ryanodine Receptors Exhibit Different Responses to Ca(2+) Overload and Luminal Ca(2+)

Spontaneous Ca(2+) release occurs in cardiac cells during sarcoplasmic reticulum Ca(2+) overload, a process we refer to as store-overload-induced Ca(2+) release (SOICR). Unlike cardiac cells, skeletal muscle cells exhibit little SOICR activity. The molecular basis of this difference is not well defi...

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Detalhes bibliográficos
Main Authors: Kong, Huihui, Wang, Ruiwu, Chen, Wenqian, Zhang, Lin, Chen, Keyun, Shimoni, Yakhin, Duff, Henry J., Chen, S. R. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Channels, Receptors, and Electrical Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831700/
https://ncbi.nlm.nih.gov/pubmed/17259277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.100545
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