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Caffeine Induces Ca(2+) Release by Reducing The Threshold for Luminal Ca(2+) Activation of the Ryanodine Receptor

Caffeine has long been used as a pharmacological probe for studying ryanodine receptor (RyR)-mediated Ca(2+) release and cardiac arrhythmias. However, the precise mechanism by which caffeine activates RyRs is elusive. Here we investigated the effects of caffeine on spontaneous Ca(2+) release and on...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kong, Huihui, Jones, Peter P., Koop, Andrea, Zhang, Lin, Duff, Henry J., Wayne Chen, S. R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747660/
https://ncbi.nlm.nih.gov/pubmed/18518861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080489
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