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Sequence of Gating Charge Movement and Pore Gating in hERG Activation and Deactivation Pathways

K(V)11.1 voltage-gated K(+) channels are noted for unusually slow activation, fast inactivation, and slow deactivation kinetics, which tune channel activity to provide vital repolarizing current during later stages of the cardiac action potential. The bulk of charge movement in human ether-a-go-go-r...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Goodchild, Samuel J., Macdonald, Logan C., Fedida, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375626/
https://ncbi.nlm.nih.gov/pubmed/25809256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.014
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