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Gating charge movement precedes ionic current activation in hERG channels

We recently reported gating currents recorded from hERG channels expressed in mammalian TSA cells and assessed the kinetics at different voltages. We detected 2 distinct components of charge movement with the bulk of the charge being carried by a slower component. Here we compare our findings in TSA...

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Detalhes bibliográficos
Main Authors: Goodchild, Samuel J, Fedida, David
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048346/
https://ncbi.nlm.nih.gov/pubmed/24126078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.26775
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