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Gating charge movement precedes ionic current activation in hERG channels

We recently reported gating currents recorded from hERG channels expressed in mammalian TSA cells and assessed the kinetics at different voltages. We detected 2 distinct components of charge movement with the bulk of the charge being carried by a slower component. Here we compare our findings in TSA...

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Bibliografiske detaljer
Main Authors: Goodchild, Samuel J, Fedida, David
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048346/
https://ncbi.nlm.nih.gov/pubmed/24126078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.26775
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