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Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels

The human ether-á-go-go–related gene (hERG) K(+) channel encodes the pore-forming α subunit of the rapid delayed rectifier current, I(Kr), and has unique activation gating kinetics, in that the α subunit of the channel activates and deactivates very slowly, which focuses the role of I(Kr) current to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Zhuren, Dou, Ying, Goodchild, Samuel J., Es-Salah-Lamoureux, Zeineb, Fedida, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607828/
https://ncbi.nlm.nih.gov/pubmed/23478995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210942
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