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Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels
The human ether-á-go-go–related gene (hERG) K(+) channel encodes the pore-forming α subunit of the rapid delayed rectifier current, I(Kr), and has unique activation gating kinetics, in that the α subunit of the channel activates and deactivates very slowly, which focuses the role of I(Kr) current to...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607828/ https://ncbi.nlm.nih.gov/pubmed/23478995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210942 |
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